White kidney bean extract, hypoglycemic effect, anti-obesity activity, cardio protective effect, anti-carcinogenic effect, anti-inflammatory activity and role on digestive health
Description : White kidney bean extract is obtained from white kidney bean, which is considered as one of the
Article Details :
White kidney bean extract is obtained from white kidney bean, which is considered as one of the most imperative and nutritious beans planted in Ancient Greece. White kidney bean extract has numerous health benefits and has been traditionally used as an effective anti-diabetic and weight loss aid.
How white kidney bean extract is prepared?
Below steps will discuss the method of preparing white kidney bean extract –
- At first the white kidney bean should be cleaned and rinsed properly
- Then it should be placed under a crushing machine to form powder
- After that it should be passed through a 60-mesh sieve
- Then it should be dissolved in water and heated at 70°C after that the effluent should be collected with a silica gel column
- Finally the effluent should be dried to obtain white kidney bean extract

Biological active components of white kidney bean extract
It contains various active components, which include –
- α-amylase blocker- it is an important lectin (carbohydrate binding protein) present in white kidney bean extract, which acts as carbohydrate blocker. Basically it helps to prevent the binding of carbohydrate to the enzyme alpha amylase, which is responsible for breaking it thus it helps to reduce the rate of carbohydrate absorption
- Trypsin and chymotrypsin blockers – these are accountable for blocking protein digestive enzymes trypsin and chymotrypsin
- Phytohemagglutinin – it is another important lectin found in white kidney bean extract, which binds with the receptors present on the intestinal lining and hinders appetite by stimulating the release of ghrelin hormone
- Saponin – it exert antioxidant activity but it also interferes with protein digestion and minerals uptake
- Phaseolin – it is considered as one of the most important and nutritious sources of amino acid
- Phytic acid – it exerts anti-carcinogenic activity and also promotes immune health but in large amount it can interfere with the absorption of nutrients and also hamper protein digestion
Mechanism of action
The main function of white kidney bean extract is focused on glycemic control. It contains α-amylase blocker that binds with α-amylase enzyme (enzyme present in saliva as well as in pancreatic juice that helps in carbohydrate digestion) and prevents the access of carbohydrates especially starch to the enzyme. As a result it has seen that carbohydrate cannot be digested and absorbed easily, which ultimately helps to decrease the risk of increasing glucose load in blood
Role of white kidney bean extract on health and disease prevention
Role on cardiac health
- Consumption of white kidney bean extract is very effective not only for promoting cardiac health but also for decreasing the prevalence of cardio vascular diseases
- It helps to reduce the concentration of homocysteine in blood. It has seen that high level of homocysteine increases the prevalence of blood vessel blockage thus its consumption is believed to be very beneficial for decreasing the risk of developing atherosclerosis and coronary artery disease by preventing blockage
Role on weight management
- As mentioned above it contains phytohemagglutinin, which is an imperative lectin that helps to suppress appetite thus it facilitates weight reduction by inhibiting over eating
- It decreases the rate of carbohydrate absorption too, which is also related with preventing obesity
- It is associated with reducing fat accumulation in body, which plays imperative role in preventing visceral obesity
Anti-inflammatory activity
- It exerts anti-inflammatory activity as well
- It helps to decrease the level of pro-inflammatory mediators in body hence reduces the prevalence of inflammation, swelling and pain
Anti-carcinogenic activity
- It helps to reduce the susceptibility of cancers by preventing gene mutation, which is considered as one of the leading causes of malignancies
- Its antioxidant activity is also responsible for protecting the body from the harmful consequences of carcinogens as it helps to destroy free radicals
- It is related with suppressing the growth of tumor cells as well as cancerous cells and also inhibits their metastasis
Hypoglycemic effects
- Individual who suffer from diabetes or who are at risk condition should include white kidney bean extract in their regular diet as it exhibits potent hypoglycemic effect
- As mentioned above it is associated with preventing the binding of carbohydrates to carbohydrate splitting enzymes thus it slows down the rate of carbohydrate digestion as well as carbohydrate absorption as a result it significantly decreases postprandial blood glucose spike
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