ALZHEIMER'S DISEASE

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VITAMIN E

Vitamin E

Fat soluble vitamin, antioxidant activity, membrane antioxidant, anti-sterility vitamin

Description :   Vitamin E, also known as tocopherol is an important naturally occurring antioxidant, which is

Article Details    :

Vitamin E, also known as tocopherol is an important naturally occurring antioxidant, which is essentially required for normal reproduction thus it is known as anti-sterility vitamin. It also exerts various other health benefits.

Chemistry

  • It is a biochemical compound, made up of tocotrienol and tocopherol group
  • 8 vitamers of Vitamin E have identified such as α tocopherol, β tocopherol, ϒ tocopherol etc among which α tocopherol is considered as the most active form of Vitamin E
  • Tocopherols are the derivatives of 6-hydroxy chromane ring, which have isoprenoid side chain
  • It is lipophilic in nature
  • Normal range of plasma tocopherol level is considered as less than 1 mg/dl
  • It can be easily destroyed by alkali, UV radiation and oxidation

Source

Foods which are rich in Vitamin E are listed below –

  • Almond
  • Peanut
  • Peanut butter
  • Sunflower oil
  • Soybean oil
  • Safflower oil
  • Beet
  • Spinach
  • Asparagus
  • Red bell pepper
  • Avocado
  • Mango
  • Sunflower seed
  • Collard greens
  • Cotton seed oil
  • Corn oil
  • Meat
  • Milk
  • Egg
  • Wheat germ oil

Vitamin E

Absorption, storage and transport of Vitamin E

  • Vitamin E requires fat and bile salt for its absorption
  • It is generally absorbed in small intestine
  • It is usually stored in adipose tissue, muscle and liver
  • It has seen that Vitamin E within liver is incorporated into lipoproteins like LDL, VLDL, HDL and transported in these form

Recommended Dietary Allowance (RDA)

  • Children of 1 to 3 years of age should consume 6mg of Vitamin E per day for fulfilling its requirement whereas children of 4 to 8 years should consume 7mg of Vitamin E per day and children of 9 to 13 years should consume 11mg of Vitamin E daily
  • Daily intake of 15mg Vitamin E is recommended for adult female but during lactation phase the requirement should be increased up to 19mg per day for meeting the increased demand of the body
  • Adult male should also consume 15mg of Vitamin E daily
  • It has seen that the intake of Vitamin E is directly related with the intake of PUFA (poly unsaturated fatty acid), generally the requirement of Vitamin E increases with increased consumption of PUFA

Health benefits

Antioxidant activity

  • It acts as potent antioxidant and helps to protect the body from oxidative damages
  • It helps to prevent non enzymatic oxidation of various important cellular components of body generally caused by free radicals, superoxide, molecular oxygen and hydrogen peroxide
  • It helps to protect PUFA from lipid peroxidation (peroxidation reaction)
  • It plays vital role in maintaining the structure and integrity of cell membrane thus Vitamin E is also known as membrane antioxidant

Role on eye health

  • Consumption of Vitamin E along with Vitamin C is very effective for improving the symptom of uveitis (swelling of eye)
  • Individual undergoes laser eye surgery should consume Vitamin E with Vitamin A for improving vision and for accelerating the healing process
  • It helps to reduce the prevalence of cataract as well

Role on nervous system

  • It plays significant role in promoting the functionality of brain as it helps to protect brain cells from oxidative damages
  • Consumption of Vitamin E is very effective for preventing ataxia, a condition, which affects the motor control adversely
  • It also helps to improve the symptoms of Alzheimer’s disease
  • It has seen that individual who consume adequate Vitamin E has lower risk of developing Parkinson’s disease
  • It plays significant role in decreasing the severity of Huntington disease (a neurological disorders that affects thinking, emotion and movement) in early stage

Role on reproductive health

  • It plays vital role in improving the efficiency of reproductive system and also helps to prevent infertility
  • It helps to maintain and preserve the germinal epithelium of gonads, which are associated with enhancing reproductive functions
  • It also helps to enhance cervical mucus, which ultimately helps the sperm to stay alive for a long period of time hence facilitates fertilization
  • It helps to protect the sperm from oxidative damages and also promotes its function

Role on preventing anemia

  • Vitamin E is an important substance found in the membrane of RBC that    Read more

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